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Top Psilocybin Retreats

LUXURY Individual/Couple Psilocybin Ceremony

Top Rated iconTop Rated
Date 2 Days Package
Center Intuitive Kasham Faro, Portugal

Lee says, "Hanna supported at the retreat I attended with Intuitive Kasham and I was able to experience first hand the care, love and support Hanna provides. She was such a pivotal part of the ceremony and was a calm, serene and sincere presence." See more

From €699
4.98
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Odyssey - Psilocybin Retreat for Healthcare Professionals

Date April 24 - 27, 2025
Center Odyssey Bend, Oregon

Natalie says, "I lost both parents over the span of a year and was having trouble navigating the grief along with the new family dynamics that were left behind. I had previous experience with homegrown psychedelics and knew how the medicine had helped in other areas of my life." See more

From $2,950 / 4 days
4.97
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5 Days with Master Class Psilocybe Mushrooms in Playa del Carmen

Date 5 Days Package
Center Xanga Guru Experiences Playa del Carmen, Mexico

Anonymous says, "I feel so fortunate to have been at this retreat with 4 other attendees whose energies collectively made the ceremony very special for my first time at a retreat of this type." See more

From $995
4.93
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Private Psilocybin Retreat

Last Chance iconLast Chance
Date April 13 - 14, 2025
Center Astraea Flora Algodonales, Spain

Alexander says, "Dominika, Anton and the whole family were so welcoming, and really got to know you and put you at ease, making you feel at home. Some gentle enquiries and full explanations of how the retreat would work." See more

€640 / 2 days
4.97
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Eleusinia 4-Day Psilocybin and DMT Weekend Retreat

Best Seller iconBest Seller
Date April 4 - 7, 2025
Center Eleusinia Valle de Bravo, Mexico

Mellissa says, "It's been less than a month since I returned home from Eleusinia and I am already wanting to go back. I spent a night on each end of the retreat in a hotel in Mexico City because I was unable to arrive and depart along the van departure schedule." See more

From $3,575 / 4 days
4.96
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Private Psilocybin Retreat - Venlo - Optional overnight stay

Date Flexible Dates

Anonymous says, "I can't emphasize enough how well-designed and structured this retreat is. The fact that it's rooted in tradition, yet not tied to any specific one, allowed me to connect with it without compromising my own beliefs." See more

From €1,000
5.00
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7 Day Psilocybin Retreat at an authentic Finca in Mexico

Date May 19 - 25, 2025
Center MexiSoul Retreats Tepatitlán de Morelos, Mexico

Damion says, "Humberto was awesome. He was very knowledgeable about the medicine and its benefits and was always available to answer any questions. He provided a very comfortable space that allowed me to come to some profound revelations concerning my family and how I see the world." See more

From $1,600 / 7 days
4.92
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3 Night Psilocybin Mushroom and Bufo (5MeO DMT) Retreat

Date May 29 - June 1, 2025
Center Arkana Spiritual Center Valle de Bravo, Mexico

Daniel says, "Recently I spent two weeks at Arkana. Originally the plan was for one week, but I extended and stayed for an additional week. Arkana was very accommodating. Although not 100% inclusive, below are the benefits that resonated the most with me." See more

From $1,980 / 4 days
5.00
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Small Group Psilocybin Ceremony

Date Open Dates
Center Mycosomatic Magic Sololá Department, Guatemala

Anonymous says, "Electing to take Psychedelics under the supervision of a stranger can be a scary concept, yet the group of humans comprising Mycosomatic Magic are so undeniably genuine that I felt safe and reassured before even meeting them." See more

From $180
5.00
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1 Day Psilocybin Therapy Session in Amsterdam

Date Open Dates
Center Inner Shift Institute Amsterdam, Netherlands

Ruben says, "In his words and deeds Lino emanates a deep tranquility and a profound gentleness which inspire within me sudden insights, a shift in perspective and inspiration." See more

€2,200
5.00
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InwardBound Costa Rican 5 day Small Group Psilocybin Retreat

Date April 24 - 28, 2025
Center Inwardbound Guanacaste Province, Costa Rica

Mark says, "The Inwardbound retreat I attended in May 2023 was my second visit having previously visited a year earlier. The team created a safe container with full support to go deeply inward which allowed me to surrender to the plant medicine ceremonies and gain really important deep insights, some of which really surprised me." See more

From €3,499 / 5 days
5.00
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1 to 1 mushroom session, near Barcelona, optional overnight stay

Date 2 Days Package
Center After the Rains Barcelona, Spain

Anonymous says, "Based at that stunning foothills of the Alpens, with the base for the retreat being an amazingly renovated farm house- the retreat is a welcome get away from the hustle and bustle of everyday life! You'll spend your days cooking, hiking, do yoga and forming a close bond with your fellow participants- all being more than ably facilitated from start to finish by Carla and Oliver- thanks both for a lovely break!" See more

$450
5.00
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Top Psilocybin Retreat Centers

How much does a Psilocybin retreat cost?

Psilocybin retreats typically cost between USD $200-900 per day, with most programs running 3-7 days. Group retreats in Mexico and Spain tend to be more affordable (USD $200-350 per day), while private or couple sessions command higher rates (USD $700-1500 per day). European retreats, particularly in the Netherlands, generally fall in the middle-to-upper price range (EUR €500-1200 per day). Factors affecting cost include accommodation quality, program duration, private vs. shared rooms, and whether the experience includes preparation and integration sessions. Location significantly impacts pricing, with legal jurisdictions like Oregon commanding premium rates.

Psilocybin Stories

Questions about Psilocybin

How does psilocybin work in the brain?

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Psilocybin is a compound found in certain mushrooms that is converted into psilocin in the body. Psilocin primarily targets serotonin (5-HT) receptors, particularly the 5-HT2A receptor.

This interaction enhances neural connectivity, leading to increased communication between different brain regions that don't typically interact. This can reduce the activity of the default mode network (DMN), a brain network associated with self-referential thoughts and sense of self. By reducing DMN activity, psilocybin induces altered states of consciousness (including visual and auditory hallucinations) while also leading to profound changes in perception, mood, and cognition.

Take a look at this study for more detailed information on how psilocybin works in the brain.

Can psilocybin help with depression and anxiety?

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Psilocybin has shown significant promise in treating depression and anxiety. Recent studies have demonstrated rapid and sustained antidepressant effects of psilocybin. For example, a study published in JAMA Psychiatry in 2023 reported psilocybin-assisted therapy led to significant reductions in depression and anxiety symptoms in patients with major depressive disorder (MDD). The antidepressant effects were rapid and sustained for several months to up to a year.

Can psilocybin play a role in treating PTSD and trauma?

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Psilocybin shows promise in treating PTSD and trauma. Research shows it can help by facilitating emotional processing and reducing avoidance behaviors associated with PTSD.

A phase 2 clinical trial of COMP360 psilocybin for PTSD found the treatment was well-tolerated with no serious adverse events along with significant improvement in symptoms over 12 weeks. Participants experienced improvements in their daily functioning and quality of life.

A 2023 study in Nature Medicine also highlighted the potential of psilocybin to reduce PTSD symptoms by promoting neuroplasticity and emotional processing. More research is needed but the early results are promising.

Can psilocybin help with addiction recovery?

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Studies have shown the benefits of psilocybin in treating various substance use disorders. For example, a clinical trial at Johns Hopkins University found that psilocybin-assisted therapy helped 80% of participants quit smoking, with continued abstinence at the six-month follow-up. Another study on alcohol use disorder showed that participants who received psilocybin had a significantly lower number of drinking days compared to those who took the placebo. Some were even able to stay away from alcohol completely.

To get the best therapeutic benefits, it typically requires multiple sessions. This includes prep and integration sessions alongside the psilocybin treatment. This holistic approach ensures that each participant can process their experiences and integrate new insights into their recovery journey.

How do psilocybin affect chronic pain management?

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Psilocybin has shown potential in managing chronic pain by affecting the brain's serotonin receptors, promoting neuroplasticity, and altering pain perception pathways. A clinical trial at the University of California, San Francisco (UCSF) is currently investigating the effectiveness of psilocybin therapy for chronic low back pain. This trial includes prep sessions, dosing sessions, and follow-up integration sessions to evaluate how psilocybin helps patients cope with chronic pain more effectively. The study aims to determine whether psilocybin therapy can improve patients' quality of life and reduce pain-related distress.

What are the potential benefits of psilocybin mushrooms for mental health?

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Psilocybin has shown significant potential benefits for overall mental health. Research has shown it can have profound therapeutic effects on various psychiatric conditions, including depression, anxiety, PTSD, and addiction.

1. Depression and Anxiety: Psilocybin therapy has demonstrated rapid and lasting reductions in symptoms of depression and anxiety. Studies, including those conducted at Johns Hopkins University, have shown that a single dose of psilocybin can produce significant antidepressant effects that last for months. This is particularly promising for treatment-resistant depression which has had little help from traditional antidepressants.

2. PTSD and Trauma: Psilocybin can help patients process traumatic memories and reduce symptoms associated with PTSD. Clinical trials are exploring its use in easing the psychological burden of trauma.

3. Addiction: Psilocybin can be effective in treating many substance use disorders and addictions. It helps by breaking down any rigid thought patterns associated with an addiction.

Research into psilocybin therapy is continuing to explore its potential to improve emotional well-being, promote cognitive flexibility, and increase openness. Not only can these effects help individuals improve their mental health, it can give them a better quality of life.

Can psilocybin mushrooms assist in coping with grief and loss?

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Psilocybin shows potential with grief and loss by promoting emotional healing and reducing psychological distress. Psilocybin-assisted therapy can enhance feelings of connectedness and bring positive emotions like joy, gratitude, and compassion. This experience can help individuals process grief, allowing them to gain new perspectives on their loss and find a path towards acceptance.

Psilocybin can also significantly reduce symptoms of depression and anxiety associated with bereavement. This therapy is still in its early stages, yet the initial findings suggest that psilocybin could be a valuable tool in helping people understand and process the complex emotions that come with grief and loss.

What clinical studies are there that support the use of psilocybin for mental health conditions?

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Here are some key clinical studies supporting the use of psilocybin for various mental health conditions:

Psilocybin for Major Depressive Disorder (MDD): A study conducted by Johns Hopkins Medicine for participants with MDD found that psilocybin therapy resulted in a significant reduction in depression severity. The effects were rapid and sustained for at least one month post-treatment.

Psilocybin-Assisted Therapy for Treatment-Resistant Depression: A study published in The New England Journal of Medicine found that psilocybin, in conjunction with psychological support, found that psilocybin was effective in treating treatment-resistant depression, showing better improvements than antidepressants.

Psilocybin for Alcohol Use Disorder: A study published in JAMA Psychiatry found that psilocybin-assisted therapy led to a reduction in alcohol consumption among participants with alcohol use disorder.

How does psilocybin compare to traditional antidepressants?

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Psilocybin has shown its ability to perform more favorably than traditional antidepressants when it comes to treating depression. A recent study found that psilocybin helped relieve many symptoms of depression and led to greater improvement.

Unlike SSRIs, which can take weeks before the effects are noticed, the effects from psilocybin were noticeable after just one or two doses. Participants of the study also maintained lower levels of depression for many weeks after their treatment.

With traditional antidepressants, there can be adverse side effects such as weight gain and sexual dysfunction, whereas any side effects from psilocybin can be resolved within a few hours. Overall, psilocybin shows lots of promise as a more effective and faster-acting alternative to antidepressants.

Can psilocybin be used to enhance creativity and problem-solving?

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According to a placebo-controlled neuroimaging study, psilocybin can increase spontaneous creative thoughts, while potentially reducing deliberate, task-focused creativity. Participants said they felt more insightful and could attack personal problems more effectively after using psilocybin. The study highlights that changes in brain connectivity were associated with these new creative insights.

Another study suggests that psychedelics like psilocybin can enhance cognitive and neural flexibility. This can help with forming new ideas and creative problem-solving. The research indicates that deliberate creativity can decrease in the short-term, however, overall creative thinking abilities improve in the long-term.

How are psilocybin mushrooms administered in therapeutic settings?

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The process for administering psilocybin mushrooms in a therapeutic setting is a carefully structured process, involving three key phases:

1. Preparation: Before the prep session, participants meet with trained therapists several times. These sessions focus on building trust, setting intentions, and preparing mentally and emotionally for the experience. This phase is crucial for creating a safe and supportive environment.

2. Dosing: During this phase, participants receive a controlled dose of psilocybin in a comfortable and aesthetically pleasing setting. It is designed to minimize stress and anxiety, and typically, there will be one or two therapists to provide guidance and support throughout the experience. Participants usually wear eye shades and listen to music to help them focus their attention inward to enhance the therapeutic benefits.

3. Integration: After the dosing session, participants meet with their therapist for multiple integration sessions. These sessions are designed to help process the experiences, gain meaningful insights, and incorporate these new insights into their daily lives. The integration phase is very important for getting the most therapeutic benefits from psilocybin.

This entire process is designed to ensure safety and efficacy. It is tailored to address important therapeutic goals, such as reducing symptoms of depression, anxiety, PTSD, or other mental health conditions.

How can someone prepare for a psilocybin experience?

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To make sure you are prepared for a psilocybin journey, there are several key aspects that should be focused on to ensure safe and meaningful sessions.

1. Set Intentions: Clearly define the purpose of the experience and what you hope to achieve. Reflect on what you can explore during your session, such as personal growth, emotional healing, or spiritual insight.

2. Create a Safe Environment: Choose a comfortable, quiet, and familiar setting that is free from potential disturbances. Make sure you feel safe and secure in the environment.

3. Select a Trusted Guide: Having a sober and experienced guide or therapist there with you can give you the reassurance and support you need. They can help you navigate challenging moments and ensure your safety.

4. Prepare Mentally and Emotionally: Try some mindfulness practices, meditation, or deep breathing exercises to calm and focus your mind. Connect with your guide to address any fears or anxiety you might have before the session.

5. Plan Logistics: Make sure you give yourself a lot of time for the experience and the integration period that follows. Avoid scheduling anything important around your session.

6. Avoid Substance Use: Do not consume alcohol or any other substances before and during the session. These can potentially interfere with the experience and outcomes.

7. Physical Preparation: Make sure you get enough rest and eat something light and nutritious before the session. Being in good physical health can also help contribute to a more positive experience.

These aspects can help people create a supportive framework for their psilocybin experience.

What should someone do if they have a bad trip with psilocybin mushrooms?

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If someone is going through a bad trip with psilocybin, the best thing to do is stay calm and remember that this is only temporary. Focus on your breathing and consider changing to a more calming environment to help shift the tone of the experience.

Turn on some soothing music and try to focus on a specific, comforting thought. If you can find someone to support and ground you through the experience, this can definitely help. Isolation can sometimes intensify the negative feelings.

Just focus on hydrating and relaxing your body as much as possible and do whatever you can to ease your mind until the experience passes.

Can psilocybin help with social anxiety disorder?

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There are some studies that look at the connection between psilocybin and social anxiety disorder, showing some potential.

Some studies show that when psilocybin is combined with mindfulness meditation, it can adjust the neural activity underlying SAD symptoms. This can help with brain connectivity, balancing activity in the salience network and improving control over the amygdala. These neural changes can reduce focus on yourself as well as negative self-perception.

This suggests that psilocybin combined with mindfulness can offer some powerful therapeutic benefits.

What is the difference between ayahuasca vs mushrooms?

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The main active compound in psilocybin mushrooms, psilocin, is actually a DMT molecule coated with compounds that 'mask' it from the MAO enzymes so that it can safely be digested and reach the bloodstream. In that way, the DMT element of the ayahuasca journey can quite fairly rival experiences with high doses of magic mushrooms.

However — the ayahuasca journey is far from only a prolonged DMT trip. It is the synergy of the B. caapi vine and the DMT admixture that catalyzes such a profoundly more full-bodied experience, one that has taken some to completely independently existing ineffable spirit realms where it's possible to meet and interact with sentient entities, or down the long, often dark road of Memory Ln, where they can revisit and confront suppressed traumatic memories.

While they also offer profound insight into the nature of the self, others, life, and the universe, mushrooms also typically tend to provide a more supportive, encouraging type of experience. Conversely, ayahuasca is infamous for holding drinkers accountable for their wrongdoings, and very clearly showing them the path toward self-betterment so that no more rationalizations are possible.

In general, ayahuasca can be said to potentially offer a more intense (both physically and mentally), exhausting, ego dissolving, profoundly transformative journey, both deeply inward as well as to exquisite alternate dimensions of existence.

Are psychedelics addictive?

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Classic psychedelics (like psilocybin mushrooms, LSD, ayahuasca, and mescaline) do not create physical dependence or addiction in the way substances like alcohol, opioids, or nicotine do. Most retreat participants find these medicines self-limiting—the profound, sometimes challenging experiences they produce naturally discourage frequent use. In traditional cultures where these plants have been used for centuries, they're typically approached with reverence and used ceremonially, not recreationally. That said, psychological attachment can form with any substance or experience that alters consciousness. At retreats, guests sometimes arrive with misconceptions about psychedelics being an easy "shortcut" to healing, only to discover these medicines often reveal what needs attention rather than instantly fixing it. The medicine itself rarely becomes problematic; the relationship with it might. What's most important isn't necessarily whether a substance can create dependency, but one's intention and the context of use. Many find these experiences so complete that they need significant integration time before feeling called to return.